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Article

Cognitive and serum BDNF correlates of BDNF Val66Met gene polymorphism in patients with schizophrenia and normal controls.

Human genetics - 1 Jul 2012

Zhang Xiang Yang, Chen Da Chun, Xiu Mei Hong, Haile Colin N, Luo Xingguang, Xu Ke, Zhang Hui Ping, Zuo Lingjun, Zhang Zhijun, Zhang Xiangrong, Kosten Therese A, Kosten Thomas R

Abstract excerpt

Studies suggest that a functional polymorphism of the brain-derived neurotrophic factor gene (BDNF Val66Met) may mediate hippocampal-dependent cognitive functions. A few studies have reported its role in cognitive deficits in schizophrenia including its association with peripheral BDNF levels as a mediator of these cognitive deficits. We assessed 657 schizophrenic inpatients and 445 healthy controls on the...

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Identifiers

PMID: 22362486
DOI: 10.1007/s00439-012-1150-x
PMCID: PMC3671849

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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