Article
Condensins promote chromosome recoiling during early anaphase to complete sister chromatid separation.
Developmental cell - 17 Aug 2010
Renshaw Matthew J, Ward Jonathan J, Kanemaki Masato, Natsume Kayo, Nédélec François J, Tanaka Tomoyuki U
Abstract excerpt
Sister chromatid separation is initiated at anaphase onset by the activation of separase, which removes cohesins from chromosomes. However, it remains elusive how sister chromatid separation is completed along the entire chromosome length. Here we found that, during early anaphase in Saccharomyces cerevisiae, sister chromatids separate gradually from centromeres to telomeres, accompanied by regional chromosome...
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