Article
Matrix metalloproteinase-3 promoter polymorphisms but not dupA-H. pylori correlate to duodenal ulcers in H. pylori-infected females.
BMC microbiology - 13 Aug 2010
Yeh Yi-Chun, Cheng Hsiu-Chi, Chang Wei-Lun, Yang Hsiao-Bai, Sheu Bor-Shyang
Abstract excerpt
BACKGROUND: This study investigated if the H. pylori dupA genotype and certain host single nucleotide polymorphisms (SNPs) of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs), including MMP-3, MMP-7, MMP-9, TIMP-1 and TIMP-2, might correlate with ulcer risk of H. pylori-infected Taiwanese patients. RESULTS: Of the 549 H. pylori-infected patients enrolled, 470 patients (265 with gastritis, 118 with...
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