Article
Association of genetic polymorphisms in IL17A and IL17F with gastro-duodenal diseases.
Journal of gastrointestinal and liver diseases : JGLD - 1 Sept 2012
Hayashi Ranji, Tahara Tomomitsu, Shiroeda Hisakazu, Matsue Yasuhiro, Minato Takahiro, Nomura Tomoe, Yamada Hideto, Saito Takashi, Matsunaga Kazuhiro, Fukuyama Tomoki, Hayashi Nobuhiko, Otsuka Toshimi, Fukumura Atsushi, Nakamura Masakastu, Tsutsumi Mikihiro, Shibata Tomoyuki, Arisawa Tomiyasu
Abstract excerpt
BACKGROUND & AIM: The important role of IL-17 in inflammatory response to Helicobacter pylori (H. pylori) colonization has been indicated. We investigated the associations between gastro-duodenal diseases and polymorphisms of IL17A (rs2275913 G>A) and IL17F (rs763780 T>C). METHODS: The study was performed in 548 subjects (363 controls and 185 peptic ulcer cases). The multiplex PCR-SSCP method was used to detect...
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