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Article

Genetic variants in matrix metalloproteinase genes are associated with development of gastric ulcer in H. Pylori infection.

The American journal of gastroenterology - 1 Jan 2006

Hellmig Stephan, Ott Stefan, Rosenstiel Phillip, Robert Fölsch Ulrich, Hampe Jochen, Schreiber Stefan

Abstract excerpt

BACKGROUND AND AIMS: Matrix metalloproteinases (MMPs) are a family of enzymes that degrade most of the macromolecules making up the extracellular matrix. H. pylori infection increases the secretion of MMPs in the gastric mucosa leading to severe mucosal damage. The aim of this study was to investigate if genetic variants in MMPs involved in the inflammatory response to H. pylori could predispose patients with...

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Identifiers

PMID: 16405530
DOI: 10.1111/j.1572-0241.2005.00348.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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