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The Intact <i>dupA</i> Cluster Is a More Reliable Helicobacter pylori Virulence Marker than <i>dupA</i> Alone

29 Oct 2011

Abstract excerpt

The duodenal ulcer promoting (dupA) gene, located in the plasticity region of Helicobacter pylori, is associated with duodenal ulcer development. dupA was predicted to form a type IV secretory system (T4SS) with vir genes around dupA (dupA cluster). We investigated the prevalence of dupA and dupA clusters and clarified associations between the dupA cluster status and clinical outcomes in the U.S. population. In...

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PMID: 22038914
DOI: 10.1128/iai.05472-11

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