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Article

Association of the functionally significant polymorphisms of the MMP9 gene with H. pylori-positive gastric ulcer in the Caucasian population of Central Russia.

PloS one - 1 Jan 2021

Dvornyk Volodymyr, Ponomarenko Irina, Minyaylo Oksana, Reshetnikov Evgeny, Churnosov Mikhail

Abstract excerpt

BACKGROUND AND PURPOSE: The study analyzed the association of functionally significant polymorphisms of matrix metalloproteinases (MMPs) genes with the development of gastric ulcer (GU) in Caucasians from Central Russia. METHODS: The 781 participants, including 434 patients with GU (196 Helicobacter pylori (H. pylori)-positive and 238 H. pylori-negative) and 347 controls (all H. pylori-negative) were recruited...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34492072
DOI: 10.1371/journal.pone.0257060
PMCID: PMC8423286

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