Article
Influence of genetic variations in ABCB1 on the clinical efficacy of ondansetron - A pharmacogenetic analysis of Pakistani population.
JPMA. The Journal of the Pakistan Medical Association - 1 Sept 2015
Farhat Kulsoom, Waheed Akbar, Hussain Azhar, Ismail Muhammad, Mansoor Qaisar, Pasha Anwar Kamal, Jafery Nusrat
Abstract excerpt
OBJECTIVE: To study the association of C1236T single-nucleotide polymorphisms of ABCB1 gene with non-responsiveness to antiemetic treatment in post-operative patients. METHODS: The prospective, clinical trial was conducted at Combined Military Hospital, Rawalpindi, and the Institute of Biomedical and Genetic Engineering, Islamabad, in 2012-13, and comprised patients undergoing elective laparoscopic...
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