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Article

Integrin &beta;4 was downregulated on the airway epithelia of asthma patients

7 Jul 2010

Abstract excerpt

The shedding of airway epithelial cells and loss of epithelial functional homeostasis are major pathological characteristics of asthma; however, the mechanism underlying these pathologies remains obscure. Our previous work showed that there were three variation sites in 5' flanking region of integrin beta4 in asthma patients, which was correlated with decreased expression of integrin beta4 in peripheral...

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Identifiers

PMID: 20705595
DOI: 10.1093/abbs/gmq058

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