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Article

The roles of integrin β<sub>4</sub> in Vascular Endothelial Cells

4 Apr 2011

Abstract excerpt

Integrin heterodimers play diverse and important roles in physiological and pathological processes, such as cell adhesion, migration, proliferation, differentiation, angiogenesis, and tumor progression, via the outside-in and/or inside-out signaling pathways. Aberrant functions of integrins have been implicated in the causation and intervention of multiple diseases. Integrin β(4), a laminin-5 (LN5) receptor,...

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PMID: 21465468
DOI: 10.1002/jcp.22769

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