Article
Integrins as Therapeutic Targets for Respiratory Diseases.
Current molecular medicine - 1 Jan 2015
Teoh C M, Tan S S L, Tran T
Abstract excerpt
Integrins are a large family of transmembrane heterodimeric proteins that constitute the main receptors for extracellular matrix components. Integrins were initially thought to be primarily involved in the maintenance of cell adhesion and tissue integrity. However, it is now appreciated that integrins play important roles in many other biological processes such as cell survival, proliferation, differentiation,...
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