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Article

SV2 regulates neurotransmitter release via multiple mechanisms.

American journal of physiology. Cell physiology - 1 Nov 2010

Nowack Amy, Yao Jia, Custer Kenneth L, Bajjalieh Sandra M

Abstract excerpt

Among the proteins that mediate calcium-stimulated transmitter release, the synaptic vesicle protein 2 (SV2) stands out as a unique modulator specific to the neurons and endocrine cells of vertebrates. In synapses, SV2 regulates the expression and trafficking of the calcium sensor protein synaptotagmin, an action consistent with the reduced calcium-mediated exocytosis observed in neurons lacking SV2. Yet SV2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20702688
DOI: 10.1152/ajpcell.00259.2010
PMCID: PMC2980308

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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