Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial proteins in neuronal degeneration.

Biochemical and biophysical research communications - 3 Sept 2004

Lindholm Dan, Eriksson Ove, Korhonen Laura

Abstract excerpt

In this review, we highlight recent findings about the role of some mitochondrial proteins in neurological diseases. Studies in mice gene-deleted for Omi/HtrA2 and AIF showed the involvement of these mitochondrial proteins in selective cell degeneration in the spinal cord and brain. In humans, mutations in the mitochondrial protein, Paraplegin, cause an autosomal form of hereditary spastic paraplegia with an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ATPases Associated with Diverse Cellular Activities
Share to Flavoproteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intracellular Membranes

Share to Ion Channels

Share to Metalloendopeptidases

Share to Nerve Degeneration

Share to Permeability

Share to Uncoupling Protein 2

Source

Identifiers

PMID: 15358091
DOI: 10.1016/j.bbrc.2004.06.138

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial proteins in neuronal degeneration.PMID 15358091Read ↗

The role of mitochondria in the pathogenesis of neurodegenerative diseases.Semantic proximity Read ↗

Neuronal degeneration and mitochondrial dysfunction.Semantic proximity Read ↗

The Impact of Mitochondrial Deficiencies in Neuromuscular DiseasesSemantic proximity Read ↗

In vivo detection of oxidized proteins: a practical approach to tissue-derived mitochondria.Semantic proximity Read ↗

Ataxia and spastic paraplegia in mitochondrial disease.Semantic proximity Read ↗

Formation of Mitochondrial Dysfunction of Nerve Cells in Cerebral Ischemia and Possibilities of Pharmacological CorrectionSemantic proximity Read ↗

A Review of Pathophysiology, Molecular Mechanisms, and Omics Approaches of Spinal Cord InjurySemantic proximity Read ↗

Data-independent acquisition-based quantitative proteomic analysis of m.3243A>G MELAS reveals novel potential pathogenesis and therapeutic targets.Semantic proximity Read ↗

Signs of early cellular dysfunction in multiple system atrophySemantic proximity Read ↗

Involvement of Mitochondria in Neurodegeneration in Multiple SclerosisSemantic proximity Read ↗

Pathogenetic mechanisms in hereditary dysfunctions of complex I of the respiratory chain in neurological diseases.Semantic proximity Read ↗

Motor neuron mitochondrial dysfunction in spinal muscular atrophySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.