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Review: Quantifying Mitochondrial Dysfunction in Complex Diseases of Aging

29 Mar 2012

Abstract excerpt

There is accumulating evidence that mitochondrial respiratory malfunction is associated with aging-associated complex diseases. However, progress in our understanding of these diseases has been hampered by the sensitivity and throughput of systems employed to quantify dysfunction and inherent limitations of the biological systems studied. In this review, we describe and contrast two methodologies that have been...

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PMID: 22459622
DOI: 10.1093/gerona/glr263

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