Genetic marker polymorphisms on chromosome 8q24 and prostate cancer in the Dutch population: DG8S737 may not be the causative variant.

doi:10.1038/ejhg.2010.133

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Article

Genetic marker polymorphisms on chromosome 8q24 and prostate cancer in the Dutch population: DG8S737 may not be the causative variant.

European journal of human genetics : EJHG - 1 Jan 2011

Zeegers Maurice P, Khan Humera S, Schouten Leo J, van Dijk Boukje A C, Goldbohm R Alexandra, Schalken Jack, Shajahan Shahin, Pearlman Alexander, Oddoux Carole, van den Brandt Piet A, Ostrer Harry

Abstract excerpt

Prostate cancer is the most commonly diagnosed cancer in men in Europe and Northern America. Genome-wide association studies (GWAS) have detected an association with markers on chromosome 8q24. Allele -8 of microsatellite DG8S737 with 22 repeats and allele A of the single-nucleotide polymorphism (SNP) rs1447295 have been found to be significantly associated with prostate cancer. As GWAS are subjected to type 1...

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PMID: 20700145
DOI: 10.1038/ejhg.2010.133
PMCID: PMC3039500

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