Article
PCR-SSO typing in HLA-disease association studies.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Jan 2000
Wordsworth P
Abstract excerpt
Associations between a large number of diseases and markers within the major histocompatibility complex (MHC) have been described. In particular, susceptibility to several autoimmune disorders, including type I diabetes mellitus and rheumatoid arthritis, is linked to genes within the MHC and strong population associations are demonstrable between certain HLA class II alleles and these conditions. Genetic mapping...
Topics
- Alleles
- Arthritis, Rheumatoid
- Autoimmune Diseases
- Celiac Disease
- DNA Probes
- Diabetes Mellitus, Type 1
- Genetic Markers
- HLA Antigens
- Histocompatibility Testing
- Humans
- Oligodeoxyribonucleotides