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Article

Skewed X chromosomal inactivation impacts T regulatory cell function in systemic sclerosis.

Annals of the rheumatic diseases - 1 Dec 2010

Broen Jasper C A, Wolvers-Tettero Ingrid L M, Geurts-van Bon Lenny, Vonk Madelon C, Coenen Marieke J H, Lafyatis Robert, Radstake Timothy R D J, Langerak Anton W

Abstract excerpt

OBJECTIVES: > To investigate the role of X chromosomal inactivation (XCI) in systemic sclerosis (SSc) and its effects on forkhead box P3 (Foxp3) expression in T regulatory cells (Tregs). METHODS: 217 women with SSc and 107 healthy women (controls) were included in the study. From these subjects,...

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Identifiers

PMID: 20699236
DOI: 10.1136/ard.2010.129999

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20699236-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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