Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Correlation between polymorphisms of the NR3C1 gene and glucocorticoid effectiveness in patients with pemphigus vulgaris.

Scientific reports - 19 Sept 2017

Fang Si-Yue, Li Chun-Lei, Liu Xiao-Song, Chen Feng, Hua Hong

Abstract excerpt

Glucocorticoid (GC) resistance is the major obscule in the treatment of pemphigus vulgaris (PV) for both patients and clinicans with unclear mechanism. A hypotheis for this resistance is the mutations or polymorphisms present in the nuclear receptor subfamily 3, group C, member 1 (NR3C1) gene that encodes receptors for steroid hormones. This study aimed to investigate the association between NR3C1 gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acid Substitution
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance

Share to Glucocorticoids

Share to Mutation, Missense

Share to Pemphigus

Share to Receptors, Glucocorticoid

Source

Open in PubMed Open full text

Identifiers

PMID: 28928407
DOI: 10.1038/s41598-017-12255-0
PMCID: PMC5605666

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Correlation between polymorphisms of the NR3C1 gene and glucocorticoid effectiveness in patients with pemphigus vulgaris.PMID 28928407Read ↗

Single-Nucleotide Nr3C1 Gene Polymorphisms Affect Glucocorticosteroid Treatment Efficacy In Patients With Pemphigus VulgarisSemantic proximity Read ↗

Lack of association between NR3C1 polymorphism and glucocorticoid resistance in Chinese patients with immune thrombocytopenia.Semantic proximity Read ↗

NR3C1 polymorphisms in Brazilians of Caucasian, African, and Asian ancestry: glucocorticoid sensitivity and genotype association.Semantic proximity Read ↗

Molecular mechanisms of glucocorticoid resistance.Semantic proximity Read ↗

Inherited genetic variants associated with glucocorticoid sensitivity in leukaemia cells.Semantic proximity Read ↗

The role of functional single nucleotide polymorphisms of the human glucocorticoid receptor gene NR3C1 in Polish patients with bronchial asthma.Semantic proximity Read ↗

Association between allelic variants of the human glucocorticoid receptor gene and autoimmune diseases: A systematic review and meta-analysis.Semantic proximity Read ↗

Glucocorticoid Resistance Syndrome: A Systematic Review of the Genotypes, Phenotypes, and Their Relationships.Semantic proximity Read ↗

Novel genetic polymorphisms in the NR3C1 (glucocorticoid receptor) gene in a Japanese population.Semantic proximity Read ↗

Association between BclI polymorphism in the NR3C1 gene and in vitro individual variations in lymphocyte responses to methylprednisolone.Semantic proximity Read ↗

Variations of the human glucocorticoid receptor gene (NR3C1): pathological and in vitro mutations and polymorphisms.Semantic proximity Read ↗

The Bcl I single nucleotide polymorphism of the human glucocorticoid receptor gene h-GR/NR3C1 promoter in patients with bronchial asthma: pilot study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.