Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of Bcl I polymorphism of the glucocorticoid receptor gene locus with response to glucocorticoids in inflammatory bowel disease

14 Aug 2007

Abstract excerpt

Glucocorticoids (GCs) are immunosuppressive drugs used for the acute treatment of patients with moderate to severe inflammatory bowel disease (IBD),1 but interindividual variability in the response to these agents is frequently observed.2 GCs diffuse freely into cells and bind to an intracellular receptor (hGR/NR3C1), so the sensitivity to these drugs may depend on the receptor number and affinity or on their...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Transport and Resistance Mechanisms
Share to Pharmaceutical studies and practices
Share to Pregnancy and Medication Impact

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17698869
DOI: 10.1136/gut.2006.116160

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of Bcl I polymorphism of the glucocorticoid receptor gene locus with response to glucocorticoids in inflammatory bowel diseasePMID 17698869Read ↗

Molecular mechanism of glucocorticoid resistance in inflammatory bowel diseaseSemantic proximity Read ↗

Genetic predictors of glucocorticoid response in pediatric patients with inflammatory bowel diseases.Semantic proximity Read ↗

Contribution of MDR1 gene polymorphisms on IBD predisposition and response to glucocorticoids in IBD in a Chinese population.Semantic proximity Read ↗

Variation in the glucocorticoid receptor gene (NR3C1) may be associated with corticosteroid dependency and resistance in children with Crohn's disease.Semantic proximity Read ↗

Characterization of the BclI Polymorphism in the Glucocorticoid Receptor GeneSemantic proximity Read ↗

Glucocorticoid receptor BclI polymorphism associates with immunomodulatory response to stress hormone in human peripheral blood mononuclear cells.Semantic proximity Read ↗

Glucocorticoid receptor gene polymorphisms in Guillain-Barré syndrome.Semantic proximity Read ↗

Bcl1 polymorphism of glucocorticoids receptor gene and bronchial asthma.Semantic proximity Read ↗

Polymorphisms in the glucocorticoid receptor gene and in the glucocorticoid-induced transcript 1 gene are associated with disease activity and response to glucocorticoid bridging therapy in rheumatoid arthritisSemantic proximity Read ↗

Some GCR Polymorphisms (N363S, ER22/23EK, and Bcl-1) May Influence Steroid-induced Toxicities and Survival Rates in Children With ALLSemantic proximity Read ↗

GLCCI1 and Glucocorticoid Receptor Genetic Diversity and Response to Glucocorticoid-Based Treatment of Graft-versus-Host Disease.Semantic proximity Read ↗

Glucocorticoid resistance in Crohn's disease and ulcerative colitis: an association study investigating GR and FKBP5 gene polymorphisms.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.