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Article

Further evidence of constrained radiation in the evolution of pathogenic Escherichia coli O157:H7.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2010

Leopold Shana R, Shaikh Nurmohammad, Tarr Phillip I

Abstract excerpt

Escherichia coli O157:H7 is a human pathogen that has emerged from its less pathogenic progenitor, E. coli O55:H7, to form the EHEC 1 clade. In its emergence, E. coli O157:H7 formed three distinct clusters, each of which exists today. Sequencing and SNP analysis of Cluster 1 of this clade demonstrated constrained radiation from the cluster founder. Here we investigated the diversity of Cluster 2 strains by...

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Identifiers

PMID: 20691811
DOI: 10.1016/j.meegid.2010.07.021
PMCID: PMC3742067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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