Article
In silico genomic analyses reveal three distinct lineages of Escherichia coli O157:H7, one of which is associated with hyper-virulence.
BMC genomics - 29 Jun 2009
Laing Chad R, Buchanan Cody, Taboada Eduardo N, Zhang Yongxiang, Karmali Mohamed A, Thomas James E, Gannon Victor Pj
Abstract excerpt
BACKGROUND: Many approaches have been used to study the evolution, population structure and genetic diversity of Escherichia coli O157:H7; however, observations made with different genotyping systems are not easily relatable to each other. Three genetic lineages of E. coli O157:H7 designated I, II and I/II have been identified using octamer-based genome scanning and microarray comparative genomic hybridization...
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