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Article

Probing genomic diversity and evolution of Escherichia coli O157 by single nucleotide polymorphisms.

Genome research - 1 Jun 2006

Zhang Wei, Qi Weihong, Albert Thomas J, Motiwala Alifiya S, Alland David, Hyytia-Trees Eija K, Ribot Efrain M, Fields Patricia I, Whittam Thomas S, Swaminathan Bala

Abstract excerpt

Infections by Shiga toxin-producing Escherichia coli O157:H7 (STEC O157) are the predominant cause of bloody diarrhea and hemolytic uremic syndrome in the United States. In silico comparison of the two complete STEC O157 genomes (Sakai and EDL933) revealed a strikingly high level of sequence identity in orthologous protein-coding genes, limiting the use of nucleotide sequences to study the evolution and...

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Identifiers

PMID: 16606700
DOI: 10.1101/gr.4759706
PMCID: PMC1473186

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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