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Article

A precise reconstruction of the emergence and constrained radiations of Escherichia coli O157 portrayed by backbone concatenomic analysis.

Proceedings of the National Academy of Sciences of the United States of America - 26 May 2009

Leopold Shana R, Magrini Vincent, Holt Nicholas J, Shaikh Nurmohammad, Mardis Elaine R, Cagno Joseph, Ogura Yoshitoshi, Iguchi Atsushi, Hayashi Tetsuya, Mellmann Alexander, Karch Helge, Besser Thomas E, Sawyer Stanley A, Whittam Thomas S, Tarr Phillip I

Abstract excerpt

Single nucleotide polymorphisms (SNPs) in stable genome regions provide durable measurements of species evolution. We systematically identified each SNP in concatenations of all backbone ORFs in 7 newly or previously sequenced evolutionarily instructive pathogenic Escherichia coli O157:H7, O157:H...

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Identifiers

PMID: 19439656
DOI: 10.1073/pnas.0812949106
PMCID: PMC2689004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19439656-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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