Article
Association of single-nucleotide polymorphisms in HLA class II/III region with knee osteoarthritis.
Osteoarthritis and cartilage - 1 Nov 2010
Shi D, Zheng Q, Chen D, Zhu L, Qin A, Fan J, Liao J, Xu Z, Lin Z, Norman P, Xu J, Nakamura T, Dai K, Zheng M, Jiang Q
Abstract excerpt
OBJECTIVE: A genome-wide association study and a replication using Japanese, Spanish and Greek Caucasian populations have recently indicated two single-nucleotide polymorphisms (SNPs) (rs7775228 and rs10947262) associated with knee Osteoarthritis (OA) susceptibility. We have further evaluated the association in knee OA subjects from Han Chinese and Australian Caucasian origin. METHODS: Two independent...
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