Association between the polymorphism of MMP-1 gene with knee osteoarthritis risk: a meta-analysis

Abstract excerpt

<title>Abstract</title> <p>Background: The existing studies on the association between polymorphisms of Matrix metalloproteinase-1 (MMP-1) (-1607 1G/2G) (rs1799750) polymorphism and the risk of knee osteoarthritis (OA, a complex multifactorial disease and a major degenerative form of arthritis) in different populations have yielded conflicting findings. <h4>Method:</h4> Literature search was performed in PubMed,...

Topics

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• Case-Control Studies
• Genetic Predisposition to Disease
• Genotype
• Matrix Metalloproteinase 1
• Matrix Metalloproteinase 13
• Matrix Metalloproteinase 3
• Osteoarthritis, Knee
• Polymorphism, Single Nucleotide

Identifiers and source

Literature Corpus work

0993041a-d924-5b2e-a412-6702e340ff5e

DOI

10.21203/rs.2.16319/v1