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Article

Engineering the enolase magnesium II binding site: implications for its evolution.

Biochemistry - 7 Sept 2010

Schreier Bettina, Höcker Birte

Abstract excerpt

The glycolytic enzyme enolase catalyzes the reversible elimination of water from 2-phosphoglycerate (2-PGA) to form phosphoenolpyruvate (PEP). Two magnesium ions in the active site are thought to facilitate the reaction by activation of the C2 proton of 2-PGA and charge stabilization of the inter...

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Source

Identifiers

PMID: 20690637
DOI: 10.1021/bi100954f

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20690637-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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