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Article

Structural Framework for Metal Incorporation during Molybdenum Cofactor Biosynthesis.

Structure (London, England : 1993) - 3 May 2016

Kasaragod Vikram Babu, Schindelin Hermann

Abstract excerpt

The molybdenum cofactor (Moco) is essential for the catalytic activity of all molybdenum-containing enzymes with the exception of nitrogenase. Moco biosynthesis follows an evolutionarily highly conserved pathway and genetic deficiencies in the corresponding human enzymes result in Moco deficiency, which manifests itself in severe neurological symptoms and death in childhood. In humans the final steps of Moco...

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Identifiers

PMID: 27112598
DOI: 10.1016/j.str.2016.02.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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