ClgR regulation of chaperone and protease systems is essential for Mycobacterium tuberculosis parasitism of the macrophage

Abstract excerpt

Chaperone and protease systems play essential roles in cellular homeostasis and have vital functions in controlling the abundance of specific cellular proteins involved in processes such as transcription, replication, metabolism and virulence. Bacteria have evolved accurate regulatory systems to control the expression and function of chaperones and potentially destructive proteases. Here, we have used a...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bacterial Genetics and Biotechnology
• Share to RNA and protein synthesis mechanisms
• Share to Tuberculosis Research and Epidemiology