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ClpB is an essential stress regulator of Mycobacterium tuberculosis and endows survival advantage to dormant bacilli

23 Jan 2020

Abstract excerpt

The ability to tolerate multiple host derived stresses, resist eradication and persist within the infected individuals is central to the pathogenicity of Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB). Mycobacterial survival is contingent upon sensing environmental perturbations and initiating a fitting response to counter them. Therefore, understanding of molecular mechanisms...

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PMID: 32014406
DOI: 10.1016/j.ijmm.2020.151402

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