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Mitigating assembly and switch errors in phased genomes of polar fishes reveals haplotype diversity in copy number of antifreeze protein genes.

Heredity - 1 Mar 2026

Moosman Owen W, Kelley Joanna L, Bogan Samuel N

Abstract excerpt

Phased genomes and pangenomes are enhancing our understanding of genetic variation. Accurate phasing and assembly in repetitive regions of the genome remain challenging, however. Addressing this obstacle is crucial for studying structural genomic variation, such as copy number variations (CNVs) common to repetitive regions. Polar fishes, for example, evolved repetitive tandem arrays of antifreeze protein (AFP)...

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PMID: 41168433
DOI: 10.1038/s41437-025-00803-8
PMCID: PMC13032017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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