Article
Failure to confirm an association between the PLXNA2 gene and schizophrenia in a Japanese population.
Progress in neuro-psychopharmacology & biological psychiatry - 9 May 2007
Fujii Takashi, Iijima Yoshimi, Kondo Hitomi, Shizuno Tomoko, Hori Hiroaki, Nakabayashi Tetsuo, Arima Kunimasa, Saitoh Osamu, Kunugi Hiroshi
Abstract excerpt
Plexins are receptors for multiple classes of semaphorins, either alone or in combination with neuropilins. Plexins participate in many cellular events that include axonal repulsion, axonal attraction, cell migration, axon pruning, and synaptic plasticity. PLXNA2 maps to chromosome 1q32. Several linkage studies reported schizophrenia susceptibility loci in the 1q22-42 region. A recent study reported that intronic...
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