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Article

On a novel coalescent model for genome-wide evolution of copy number variations.

International journal of data mining and bioinformatics - 1 Jan 2010

Mitrofanova Antonina, Mishra Bhubaneswar

Abstract excerpt

Since we are limited in our knowledge of human demographic history and variations of recombination and mutation rates, large-scale computer simulation is a necessary tool in genetics. Here we propose and computationally simulate a model of evolution for unique and segmentally duplicated regions of human genome. Since such segmentally duplicated regions show a complex behaviour of copy number changes, our model...

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PMID: 20681481
DOI: 10.1504/ijdmb.2010.033522

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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