Article
The coalescent with selection on copy number variants.
Genetics - 1 Mar 2012
Teshima Kosuke M, Innan Hideki
Abstract excerpt
We develop a coalescent-based simulation tool to generate patterns of single nucleotide polymorphisms (SNPs) in a wide region encompassing both the original and duplicated genes. Selection on the new duplicated copy and interlocus gene conversion between the two copies are incorporated. This simulation enables us to explore how selection on duplicated copies affects the pattern of SNPs. The fixation of an...
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