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Article

Transgenic mice expressing an artificial zinc finger regulator targeting an endogenous gene.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010

Passananti Claudio, Corbi Nicoletta, Onori Annalisa, Di Certo Maria Grazia, Mattei Elisabetta

Abstract excerpt

Zinc finger (ZF) proteins belonging to the Cys2-His2 class provide a simple and versatile framework to design novel artificial transcription factors (ATFs) targeted to the desired genes. Our work is based on ZF ATFs engineered to up-regulate the expression level of the dystrophin-related gene utr...

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Source

Identifiers

PMID: 20680835
DOI: 10.1007/978-1-60761-753-2_11

Genes

DMD
GCG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20680835-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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