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Article

Finding of a highly efficient ZFN pair for Aqpep gene functioning in murine zygotes.

The Journal of reproduction and development - 1 Jan 2015

Fujii Wataru, Onuma Asuka, Yoshioka Shin, Nagashima Keisuke, Sugiura Koji, Naito Kunihiko

Abstract excerpt

The generation efficiencies of mutation-induced mice when using engineered zinc-finger nucleases (ZFNs) have been generally 10 to 20% of obtained pups in previous studies. The discovery of high-affinity DNA-binding modules can contribute to the generation of various kinds of novel artificial chromatin-targeting tools, such as zinc-finger acetyltransferases, zinc-finger histone kinases and so on, as well as...

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Identifiers

PMID: 26460691
DOI: 10.1262/jrd.2015-087
PMCID: PMC4685226

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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