Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The expression of the secreted aspartyl proteinases Sap4 to Sap6 from <i>Candida albicans</i> in murine macrophages

1 Apr 1998

Abstract excerpt

Medically important yeasts of the genus Candida secrete aspartyl proteinases (Sap), which are of particular interest as virulence factors. Six closely related gene sequences, SAP1 to SAP6, for secreted proteinases are present in Candida albicans. The methylotrophic yeast Pichia pastoris was chosen as an expression system for preparing substantial amounts of each Sap isoenzyme. Interestingly, Sap4, Sap5 and Sap6,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antifungal resistance and susceptibility
Share to Fungal Infections and Studies
Share to Peptidase Inhibition and Analysis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9632257
DOI: 10.1046/j.1365-2958.1998.00815.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The expression of the secreted aspartyl proteinases Sap4 to Sap6 from <i>Candida albicans</i> in murine macrophagesPMID 9632257Read ↗

Aspartyl proteinases of<i>Candida albicans</i>and their role in pathogenicitySemantic proximity Read ↗

<i>Candida albicans</i>Secreted Aspartyl Proteinases in Virulence and PathogenesisSemantic proximity Read ↗

A triple deletion of the secreted aspartyl proteinase genes SAP4, SAP5, and SAP6 of Candida albicans causes attenuated virulenceSemantic proximity Read ↗

[What functions do six different genes for secretory proteinases have in Candida albicans?].Semantic proximity Read ↗

Secreted Aspartyl Proteases Family: A Perspective Review on the Regulation Of Fungal PathogenesisSemantic proximity Read ↗

The Role of Secreted Aspartyl Proteinases in<i>Candida albicans</i>KeratitisSemantic proximity Read ↗

Candida albicans proteinases and host/pathogen interactionsSemantic proximity Read ↗

Candida albicans possesses Sap7 as a pepstatin A-insensitive secreted aspartic protease.Semantic proximity Read ↗

Different isoforms of secreted aspartyl proteinases (Sap) are expressed by Candida albicans during oral and cutaneous candidosis in vivoSemantic proximity Read ↗

X‐ray structures of Sap1 and Sap5: Structural comparison of the secreted aspartic proteinases from <i>Candida albicans</i>Semantic proximity Read ↗

Candida albicans secreted aspartyl proteinases: isoenzyme pattern is determined by cell type, and levels are determined by environmental factorsSemantic proximity Read ↗

Secreted aspartic proteinase (Sap) activity contributes to tissue damage in a model of human oral candidosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.