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Article

Secreted aspartic proteinase (Sap) activity contributes to tissue damage in a model of human oral candidosis.

Molecular microbiology - 1 Oct 1999

Schaller M, Korting H C, Schäfer W, Bastert J, Chen W, Hube B

Abstract excerpt

Secreted aspartic proteinases (Saps) are important virulence factors during Candida albicans mucosal or disseminated infections. A differential expression of individual SAP genes has been shown previously in a model of oral candidosis based on reconstituted human epithelium (RHE), and in the oral cavity of patients. In this study, the ultrastructural localization of distinct groups of Sap isoenzymes expressed...

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Share to Antigens, Fungal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10540295
DOI: 10.1046/j.1365-2958.1999.01590.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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