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Article

Different roles of DosS and DosT in the hypoxic adaptation of Mycobacteria.

Journal of bacteriology - 1 Oct 2010

Kim Min-Ju, Park Kwang-Jin, Ko In-Jeong, Kim Young Min, Oh Jeong-Il

Abstract excerpt

The DosS (DevS) and DosT histidine kinases form a two-component system together with the DosR (DevR) response regulator in Mycobacterium tuberculosis. DosS and DosT, which have high sequence similarity to each other over the length of their amino acid sequences, contain two GAF domains (GAF-A and GAF-B) in their N-terminal sensory domains. Complementation tests in conjunction with phylogenetic analysis showed...

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Share to Bacterial Proteins
Share to Cell Hypoxia
Share to Genetic Complementation Test

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Models, Genetic

Share to Mutagenesis, Site-Directed

Share to Mycobacterium smegmatis

Share to Reverse Transcriptase Polymerase Chain Reaction

Share to Sequence Homology, Amino Acid

Source

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Identifiers

PMID: 20675480
DOI: 10.1128/JB.00550-10
PMCID: PMC2944544

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Different roles of DosS and DosT in the hypoxic adaptation of Mycobacteria.PMID 20675480Read ↗

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