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Article

A two-component regulator of universal stress protein expression and adaptation to oxygen starvation in Mycobacterium smegmatis.

Journal of bacteriology - 1 Mar 2003

O'Toole Ronan, Smeulders Marjan J, Blokpoel Marian C, Kay Emily J, Lougheed Kathryn, Williams Huw D

Abstract excerpt

We identified a response regulator in Mycobacterium smegmatis which plays an important role in adaptation to oxygen-starved stationary phase. The regulator exhibits strong sequence similarity to DevR/Rv3133c of M. tuberculosis. The structural gene is present on a multigene locus, which also encodes a sensor kinase. A devR mutant of M. smegmatis was adept at surviving growth arrest initiated by either carbon or...

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Identifiers

PMID: 12591871
DOI: 10.1128/JB.185.5.1543-1554.2003
PMCID: PMC148059

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A two-component regulator of universal stress protein expression and adaptation to oxygen starvation in Mycobacterium smegmatis.PMID 12591871Read ↗

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