Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gestational low protein diet in the rat mediates<i>Igf2</i>gene expression in male offspring via altered hepatic DNA methylation

1 Oct 2010

Abstract excerpt

Biological responses to environmental stress, including nutrient limitation are mediated in part by epigenetic modifications including DNA methylation. Insulin-like growth factor II (Igf2) and H19 are subject to epigenetic modifications leading to genomic imprinting. The present study was designed to test the effect of maternal low protein diet on the Igf2/H19 locus in offspring. Pregnant Sprague-Dawley rats were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Birth, Development, and Health
Share to Epigenetics and DNA Methylation
Share to Genetic Syndromes and Imprinting

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20671425
DOI: 10.4161/epi.5.7.12882

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gestational low protein diet in the rat mediates<i>Igf2</i>gene expression in male offspring via altered hepatic DNA methylationPMID 20671425Read ↗

Imprinted gene expression in the rat embryo–fetal axis is altered in response to periconceptional maternal low protein dietSemantic proximity Read ↗

Epigenetics of programmed obesity: alteration in IUGR rat hepatic IGF1 mRNA expression and histone structure in rapid vs. delayed postnatal catch-up growthSemantic proximity Read ↗

Association of maternal and nutrient supply line factors with DNA methylation at the imprinted <i>IGF2/H19</i> locus in multiple tissues of newborn twinsSemantic proximity Read ↗

Igf2-H19, an imprinted tandem gene, is an important regulator of embryonic development, a guardian of proliferation of adult pluripotent stem cells, a regulator of longevity, and a ‘passkey’ to cancerogenesisSemantic proximity Read ↗

A methyl‐deficient diet modifies histone methylation and alters <i>Igf2</i> and <i>H19</i> repression in the prostateSemantic proximity Read ↗

Post-weaning diet affects genomic imprinting at the insulin-like growth factor 2 (Igf2) locus.Semantic proximity Read ↗

Maternal Diet during Pregnancy Induces Gene Expression and DNA Methylation Changes in Fetal Tissues in SheepSemantic proximity Read ↗

Higher Hepatic miR-29 Expression in Undernourished Male Rats During the Postnatal Period Targets the Long-Term Repression of IGF-1Semantic proximity Read ↗

Alterations in expression of imprinted genes from the H19/IGF2 loci in a multigenerational model of intrauterine growth restriction (IUGR)Semantic proximity Read ↗

Imprinted Genes, Placental Development and Fetal GrowthSemantic proximity Read ↗

IGF2 DNA methylation is a modulator of newborn’s fetal growth and developmentSemantic proximity Read ↗

Epigenetic regulation of the <i>Igf2/H19</i> gene clusterSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.