Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Post-weaning diet affects genomic imprinting at the insulin-like growth factor 2 (Igf2) locus.

Human molecular genetics - 1 Mar 2006

Waterland Robert A, Lin Juan-Ru, Smith Charlotte A, Jirtle Randy L

Abstract excerpt

IGF2 loss of imprinting (LOI) is fairly prevalent and implicated in the pathogenesis of human cancer and developmental disease; however, the causes of this phenomenon are largely unknown. We determined whether the post-weaning diet of mice affects allelic expression and CpG methylation of Igf2. C57BL/6JxCast/EiJ F1 hybrid mice were weaned onto (1) a standard natural ingredient control diet, (2) a synthetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatography, High Pressure Liquid
Share to CpG Islands

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genomic Imprinting

Share to Insulin-Like Growth Factor II

Share to Kidney

Share to Mice, Inbred Strains

Share to Random Allocation

Source

Identifiers

PMID: 16421170
DOI: 10.1093/hmg/ddi484

Genes

IGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Post-weaning diet affects genomic imprinting at the insulin-like growth factor 2 (Igf2) locus.PMID 16421170Read ↗

IGF2: Development, Genetic and Epigenetic AbnormalitiesSemantic proximity Read ↗

Advanced aging phenotype is revealed by epigenetic modifications in rat liver after in utero malnutrition.Semantic proximity Read ↗

Epigenetics of programmed obesity: alteration in IUGR rat hepatic IGF1 mRNA expression and histone structure in rapid vs. delayed postnatal catch-up growthSemantic proximity Read ↗

Gestational low protein diet in the rat mediates<i>Igf2</i>gene expression in male offspring via altered hepatic DNA methylationSemantic proximity Read ↗

Non-imprinted Igf2r expression decreases growth and rescues the Tme mutation in mice.Semantic proximity Read ↗

DNA methylation at differentially methylated regions of imprinted genes is resistant to developmental programming by maternal nutritionSemantic proximity Read ↗

Prenatal exposure to tobacco smoke sex dependently influences methylation and mRNA levels of the Igf axis in lungs of mouse offspringSemantic proximity Read ↗

The imprinted Zdbf2 gene finely tunes control of feeding and growth in neonatesSemantic proximity Read ↗

Tissue-specific imprinting of the mouse insulin-like growth factor II receptor gene correlates with differential allele-specific DNA methylation.Semantic proximity Read ↗

The insulin-like growth factor type-2 receptor gene is imprinted in the mouse but not in humans.Semantic proximity Read ↗

Imprint switch mutations at Rasgrf1 support conflict hypothesis of imprinting and define a growth control mechanism upstream of IGF1.Semantic proximity Read ↗

Perturbations to the IGF1 growth pathway and adult energy homeostasis following disruption of mouse chromosome 12 imprinting.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.