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IGF2 DNA methylation is a modulator of newborn’s fetal growth and development

6 Sept 2012

Abstract excerpt

The insulin-like growth factor 2 (IGF2) gene, located within a cluster of imprinted genes on chromosome 11p15, encodes a fetal and placental growth factor affecting birth weight. DNA methylation variability at the IGF2 gene locus has been previously reported but its consequences on fetal growth and development are still mostly unknown in normal pediatric population. We collected one hundred placenta biopsies from...

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PMID: 22907587
DOI: 10.4161/epi.21855

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