Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene dosage of the common variant 9p21 predicts severity of coronary artery disease.

Journal of the American College of Cardiology - 3 Aug 2010

Dandona Sonny, Stewart Alexandre F R, Chen Li, Williams Kathryn, So Derek, O'Brien Ed, Glover Christopher, Lemay Michel, Assogba Olivia, Vo Lan, Wang Yan Qing, Labinaz Marino, Wells George A, McPherson Ruth, Roberts Robert

Abstract excerpt

OBJECTIVES: The purpose of this study was to test the hypothesis that 9p21 gene dosage determines the severity of coronary artery disease (CAD). BACKGROUND: The 9p21 locus is the first common genetic variant to associate with risk of CAD and/or myocardial infarction in multiple studies. METHODS: A cross-sectional study examined nondiabetic patients with CAD defined by coronary angiography to have at least 1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Chromosomes, Human, Pair 9

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Coronary Angiography

Share to Coronary Artery Disease

Share to Electrocardiography

Share to Gene Dosage

Share to Ontario

Share to Severity of Illness Index

Source

Identifiers

PMID: 20670758
DOI: 10.1016/j.jacc.2009.10.092

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene dosage of the common variant 9p21 predicts severity of coronary artery disease.PMID 20670758Read ↗

Variants in 9p21 Predicts Severity of Coronary Artery Disease in a Chinese Han Population.Semantic proximity Read ↗

Association between the chromosome 9p21 locus and angiographic coronary artery disease burden: a collaborative meta-analysis.Semantic proximity Read ↗

A customized genetic approach to the number one killer: coronary artery disease.Semantic proximity Read ↗

Translating genomic analyses into improved management of coronary artery disease.Semantic proximity Read ↗

Variant on 9p21 is strongly associated with coronary artery disease but lacks association with myocardial infarction and disease severity in a population in Western India.Semantic proximity Read ↗

9p21 and the genetic revolution for coronary artery disease.Semantic proximity Read ↗

Genetic variation at the 9p21 locus predicts angiographic coronary artery disease prevalence but not extent and has clinical utility.Semantic proximity Read ↗

The association of 9p21-3 locus with coronary atherosclerosis: a systematic review and meta-analysis.Semantic proximity Read ↗

The 9p21 susceptibility locus for coronary artery disease and the severity of coronary atherosclerosis.Semantic proximity Read ↗

9p21 is a shared susceptibility locus strongly for coronary artery disease and weakly for ischemic stroke in Chinese Han population.Semantic proximity Read ↗

Evaluation of association between common genetic variants on chromosome 9p21 and coronary artery disease in Turkish population.Semantic proximity Read ↗

The chromosome 9p21 risk locus is associated with angiographic severity and progression of coronary artery disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.