Article
Association between the chromosome 9p21 locus and angiographic coronary artery disease burden: a collaborative meta-analysis.
Journal of the American College of Cardiology - 5 Mar 2013
Chan Kenneth, Patel Riyaz S, Newcombe Paul, Nelson Christopher P, Qasim Atif, Epstein Stephen E, Burnett Susan, Vaccarino Viola L, Zafari A Maziar, Shah Svati H, Anderson Jeffrey L, Carlquist John F, Hartiala Jaana, Allayee Hooman, Hinohara Kunihiko, Lee Bok-Soo, Erl Anna, Ellis Katrina L, Goel Anuj, Schaefer Arne S, El Mokhtari Nour Eddine, Goldstein Benjamin A, Hlatky Mark A, Go Alan S, Shen Gong-Qing, Gong Yan, Pepine Carl, Laxton Ross C, Whittaker John C, Tang W H Wilson, Johnson Julie A, Wang Qing K, Assimes Themistocles L, Nöthlings Ute, Farrall Martin, Watkins Hugh, Richards A Mark, Cameron Vicky A, Muendlein Axel, Drexel Heinz, Koch Werner, Park Jeong Euy, Kimura Akinori, Shen Wei-feng, Simpson Iain A, Hazen Stanley L, Horne Benjamin D, Hauser Elizabeth R, Quyyumi Arshed A, Reilly Muredach P, Samani Nilesh J, Ye Shu
Abstract excerpt
OBJECTIVES: This study sought to ascertain the relationship of 9p21 locus with: 1) angiographic coronary artery disease (CAD) burden; and 2) myocardial infarction (MI) in individuals with underlying CAD. BACKGROUND: Chromosome 9p21 variants have been robustly associated with coronary heart disease, but questions remain on the mechanism of risk, specifically whether the locus contributes to coronary atheroma...
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