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Article

Merlin inhibits neurite outgrowth in the CNS.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 28 Jul 2010

Schulz Alexander, Geissler Katja J, Kumar Sujeet, Leichsenring Gregor, Morrison Helen, Baader Stephan L

Abstract excerpt

The neurofibromatosis type 2 gene product merlin is known to provoke gliogenic tumors as a result of its mutagenic loss. Merlin's physiological anti-mitogenic function makes it unique among its ezrin-radixin-moesin (ERM) family members. Although ERM proteins and merlin are known to be expressed in glial cells of the peripheral nervous system and CNS, the neuronal expression pattern and function of merlin have...

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Identifiers

PMID: 20668201
DOI: 10.1523/JNEUROSCI.0840-10.2010
PMCID: PMC6633373

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Merlin inhibits neurite outgrowth in the CNS.PMID 20668201Read ↗

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MIR Is a Novel ERM-like Protein That Interacts with Myosin Regulatory Light Chain and Inhibits Neurite OutgrowthSemantic proximity Read ↗

Merlin/Neurofibromatosis Type 2 Suppresses Growth by Inhibiting the Activation of Ras and RacSemantic proximity Read ↗

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Characterization of the NF2 protein merlin and the ERM protein ezrin in human, rat, and mouse central nervous systemSemantic proximity Read ↗

The Neurofibromatosis 2 Protein, Merlin, Regulates Glial Cell Growth in an ErbB2- and Src-Dependent MannerSemantic proximity Read ↗

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