Screening of Predicted Secreted Antigens from <i>Mycobacterium bovis</i> Identifies Potential Novel Differential Diagnostic Reagents

Abstract excerpt

To date, the most promising vaccination strategies for the control of bovine tuberculosis (TB) focus on improving the efficacy of Mycobacterium bovis bacillus Calmette-Guérin (BCG). However, vaccination with BCG results in sensitization of animals to bovine tuberculin and compromises tests currently used for diagnosis of bovine TB infection. Thus, the development of specific diagnostic reagents capable of...