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Systems Biology Approach Predicts Antibody Signature Associated with<i>Brucella melitensis</i>Infection in Humans

25 Aug 2011

Abstract excerpt

A complete understanding of the factors that determine selection of antigens recognized by the humoral immune response following infectious agent challenge is lacking. Here we illustrate a systems biology approach to identify the antibody signature associated with Brucella melitensis (Bm) infection in humans and predict proteomic features of serodiagnostic antigens. By taking advantage of a full proteome...

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PMID: 21863892
DOI: 10.1021/pr200619r

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