Article
Screening of Predicted Secreted Antigens fromMycobacterium bovisReveals the Immunodominance of the ESAT-6 Protein Family
20 Jan 2010
Abstract excerpt
Results of previous studies utilizing bioinformatic approaches in antigen-mining experiments revealed that secreted proteins are among the most frequently recognized antigens from Mycobacterium bovis. Thus, we hypothesized that the analysis of secreted proteins is likely to reveal additional immunogenic antigens that can be used to increase the specificity of diagnostic tests or be suitable vaccination candidates...
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