Article
Genomic Approach to Identification of Mycobacterium bovis Diagnostic Antigens in Cattle
1 Aug 2003
Abstract excerpt
Differential delayed-type hypersensitivity skin testing with tuberculin purified protein derivatives from Mycobacterium bovis and M. avium is the standard for diagnosing bovine tuberculosis. However, improved tests based on defined, specific antigens are urgently needed. In the present study, a combination of bioinformatics, molecular biology, and bovine models of infection were used to screen mycobacterial...
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