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Article

A new cistron in the murine hepatitis virus replicase gene.

Journal of virology - 1 Oct 2010

Stokes Helen L, Baliji Surendranath, Hui Chang Guo, Sawicki Stanley G, Baker Susan C, Siddell Stuart G

Abstract excerpt

We report an RNA-negative, temperature-sensitive (ts) mutant of Murine hepatitis virus, Bristol ts31 (MHV-Brts31), that defines a new complementation group within the MHV replicase gene locus. MHV-Brts31 has near-normal levels of RNA synthesis at the permissive temperature of 33 degrees C but is unable to synthesize viral RNA when the infection is initiated and maintained at the nonpermissive temperature of 39.5...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20668085
DOI: 10.1128/JVI.00901-10
PMCID: PMC2937787

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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